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Fancy Grilled Cheese Sandwich Casserole

This fancy grilled cheese sandwich casserole takes all the flavors of your favorite childhood sandwich and turns it into an easy, one-pot meal.

Easy Budget-Friendly Meal

Is there anything more comforting than a grilled cheese sandwich? Whether you’re feeding a hungry family or want something special for yourself, this dish is sure to hit the spot.

It’s perfect for feeding a crowd for brunch too.

Old-Fashioned Grilled cheese sandwiches are a classic comfort food. But sometimes, grilled cheese can be a little bit boring. That’s where this casserole comes in.

This easy recipe transforms your favorite sandwich into an all-in-one meal that the whole family will love. So next time you’re in the mood for some cheesy goodness, give this casserole a try.

Fancy Cheese Sandwich Casserole

Grilled Cheese Recipe in the Oven

For years I had a cast iron skillet on the stovetop to get just lunch on the table for everyone to eat together. Even then, some would start with their soup first as it was difficult to fit more than two sandwiches in the pan. Even then, making two sandwiches at a time in a skillet are hard to make as it is hard to flip them.

Therefore, when I first made this upscale grilled cheese sandwich in the oven, it was a game changer. We still got the cheesy, crispy bread texture, but with this casserole, it is a bit heartier and more filling.

For this oven baked grilled cheese recipe, just layer in your bread, cheese, and bread again. Then mix your liquid ingredients and pour over the top and bake.

Easy Weeknight meal - cheese sandwich

Sheet Pan Grilled Cheese

Another option for you if you just want a regular grilled cheese is to use a sheet pan versus a 9 x 13 baking pan and omit the liquid ingredients.

 Just butter the bread, lay the slices of bread on the sheet pan with the buttered side down. Add your cheese slices and top with another slice of buttered bread with the butter facing up. Bake until there is gooey cheese and golden, crispy bread. Bake for about 10-15 minutes at 350 degrees Fahrenheit.

Recipe Variations

This easy recipe makes the best cheese sandwich. However, you can mix things up to your liking. Make this an ultimate gourmet meal or keep it simple for a simple comforting meal.

Here are a few ways to mix things up.

Different Types of Cheeses:

  • American Cheese
  • White Cheddar Cheese
  • Sharp Cheddar Cheese
  • Monterey Jack Cheese
  • Swiss Cheese
  • Muenster Cheese
  • Colby Cheese
  • Smoked Gouda Cheese
  • Or use a combination of cheeses.
layering the grilled cheese casserole ingredients

Different Types of Breads:

  • White Bread
  • Wheat Bread
  • Sourdough bread
  • Butter Topped Bread
  • Challah Bread
  • Crusty Bread that is Day Old

Take it to the next level and add:

  • Caramelized Onions
  • Thinly Sliced Red Onions
  • Thinly Sliced Apples
  • Red peppers
  • Fried Bacon
  • Ham Slices

Another way to take your grilled cheese sandwich to the next level is fig jam or Dijon mustard.

Sides for Grilled Cheese

Grilled Cheese Sandwiches pair well with creamy tomato soup, tomato bisque, or creamed vegetables. Start with a refreshing salad for a delicious meal. However, there are so many other soup options that are tasty with this dish. Here are a few that we love.

This creamy bacon potato corn soup is simple, ultra-creamy and comforting.

This unique delicious chili offers the sweet and robust tomato flavors that you love from spaghetti, but with the kick of classic chili.

This easy recipe for Creamy Meatball Soup will have you feeling warm and cozy.

Berry Spring Salad with Maple Vinaigrette

Strawberry Spring Mix Salad with Oriental Dressing

Few things in life are as satisfying as a good batch of homemade potato chips

How to Make Homemade French Fries

How to Reheat Grilled Cheese

The quickest way to reheat a grilled cheese sandwich and get a crispy, toasty outside and melty cheese inside is to use a frying pan.

Start with a frying pan on the stovetop using medium heat allow the pan to warm for a minutes before adding the sandwich.

While the pan is heating, spread a thin layer of butter of mayonnaise on the outside of the grilled cheese.

Add the sandwich to the pan and cover with a lid. This helps melt the cheese faster.

After 1-2 minutes, flip the sandwich and cook another 1-2 minutes with the lid off. This allows the bread to crisp.

Once the bread has crisped to your desired crispiness, remove from the pan and enjoy.

Fancy Cheese Sandwich Casserole
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Fancy Grilled Cheese Sandwich Casserole

This fancy grilled cheese sandwich casserole takes all the flavors of your favorite childhood sandwich and turns it into an easy, one-pot meal. Easy Budget-Friendly Meal
Prep Time10 minutes
Cook Time1 hour
Total Time1 hour 10 minutes
Course: Dinner, lunch
Cuisine: American
Keyword: brunch casserole, easy recipe, Gameday food
Servings: 6 Servings
Calories: 413kcal

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  • 12 Slices Bread any kind
  • 6 Slices Cheddar Cheese
  • 6 Ounces Muenster Cheese Shredded
  • 2 Large Eggs beaten
  • 2 ½ Cups Milk
  • 1 Teaspoon Salt
  • 1/4 Teaspoon Black Pepper
  • ¼ Teaspoon Dry Mustard
  • ¼ Teaspoon Paprika


  • In a 9 X 13 baking pan sprayed with cooking spray, arrange 6 slices of the bread.
  • Arrange the cheddar cheese slices on top of the bread. Add the shredded Muenster Cheese on top of that.
  • Top with the remaining six bread slices.
  • In a separate bowl, add the milk, eggs, salt, black pepper, dry mustard, and paprika. Whisk to combine.
  • Pour over the mixture over the bread and cheese.
  • Bake at 350 degrees Fahrenheit for 45-50 minutes or until the bread is golden brown and crispy on top.

Your Own Private Notes


Calories: 413kcal | Carbohydrates: 32g | Protein: 22g | Fat: 22g | Saturated Fat: 11g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 5g | Trans Fat: 0.02g | Cholesterol: 118mg | Sodium: 1004mg | Potassium: 308mg | Fiber: 2g | Sugar: 9g | Vitamin A: 720IU | Vitamin C: 0.4mg | Calcium: 529mg | Iron: 2mg


You can find Victoria crocheting, quilting, and creating recipes. She has cooked in restaurants for over 20 years, including many larger parties. In her professional career, she has worked in management in a wide variety of businesses including higher education as a dean of a division. All the while attending college part-time to achieve her doctorate in higher education with an emphasis in e-learning.

5 from 2 votes (2 ratings without comment)

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